Genes in your email? Why not?

Hyungwon Kang / Reuters file

Genomics pioneer Craig Venter, seen here during a congressional hearing in 2010, says his team is working on a system to convert genetic code into a digital file that could be sent via email.


Someday, genetic code may be as downloadable and potentially shareable as email, thanks to devices that can translate biological material into digital files, and vice versa. That's the vision that J. Craig Venter, a pioneer in the field of synthetic biology, laid out last week at Trinity College Dublin as part of Euroscience Open Forum 2012.

Venter's talk — titled "What Is Life?" — was intended as a follow up on physicist Erwin Schrödinger's 1943 lecture in Dublin on the same topic. That earlier lecture was seen as foreshadowing the age of genetics and the discovery of DNA's double-helix structure a decade later. Venter's talk sketched out a 21st-century vision in which the code of life is seen as merely another kind of software.


"All living cells that we know of on this planet are 'DNA software'-driven biological machines comprised of hundreds of thousands of protein robots, coded for by the DNA, that carry out precise functions," New Scientist quoted Venter as saying. "We are now using computer software to design new DNA software."

Venter said he and his colleagues are now designing the software for three different types of microbial organisms. Once the digital designs are finished, they'll be fed into DNA sequencing machines to create the corresponding chemical code. The genetic software would then be inserted into hollowed-out cells to kick-start the machinery of life. "I am hoping it will happen this year," the Irish Times quoted Venter as saying.

His aim is to produce microbes that are custom-designed create biofuel, foodstuffs or pharmaceuticals. Using today's technology, researchers can collaborate on genetic design by converting the four-base code of a DNA molecule into a standardized digital file and then sending the file to another lab, where it's converting back into DNA molecules. Venter talked of developing a miniaturized digital-biological converter that could do the trick, Forbes India reported. The concept could lead to technologies that streamline the creation of synthetic organisms, just as 3-D printers are streamlining the creation of synthetic shapes

"This is biology moving at the speed of light," Venter said.

Can policymakers keep pace? A progress report from the Synthetic Biology Project at the Woodrow Wilson International Center for Scholars suggests that's debatable. Today the project updated its "Synthetic Biology Scorecard," saying that federal agencies have started taking steps to address a set of policy recommendations issued 18 months ago — but haven't yet fully addressed any of those recommendations.

On the plus side, federal officials have set up an interagency working group on synthetic biology, have participated in international meetings on the issues surrounding synthetic biology, and have drawn up a National Bioeconomy Blueprint. But the project says there's been no federal activity to review public funding for synthetic biology research, assess the risks associated with releasing synthetic organisms outside the lab, or evaluate moral objections to the technology.

Will synthetic biology open the door to a brave new world? An ethical and environmental morass? Both, or neither? Feel free to weigh in with your comments below.

More about synthetic biology:


Alan Boyle is NBCNews.com's science editor. Connect with the Cosmic Log community by "liking" the log's Facebook page, following @b0yle on Twitter and adding the Cosmic Log page to your Google+ presence. To keep up with Cosmic Log as well as NBCNews.com's other stories about science and space, sign up for the Tech & Science newsletter, delivered to your email in-box every weekday. You can also check out "The Case for Pluto," my book about the dwarf planet and the search for new worlds.

Discuss this post

Mother Nature had many many years of trial and error to make sure the DNA of every creature worked well with the environment and with other species. There are far too many variables in DNA, and the results from changing them to ever be sure that unintended bad consequences do not happen. We are at an infancy at playing with DNA. If we do not respect what can happen if we tinker too much, then whole ecosystems could be put in danger, or worse.

  • 1 vote
Reply#1 - Tue Jul 17, 2012 12:37 AM EDT

Such as might be what happens when you mix radiation with DNA. I feel we already dabble in changing DNA every time a child is conceived. We really don't know how long it took for us to become the mammals we are. There are too many missing links. If evolution is what you believe in. As for being able to email our genetic code, that sounds to me like someone wants us to have a global number that can only be duplicated through cloning.

  • 1 vote
#1.1 - Tue Jul 17, 2012 3:10 AM EDT

I'm less concerned about artificially created DNA affecting Human DNA and more about how many times it will take for natural bacteria and viruses combine with these unique DNA strands to create something truly dangerous.

It only takes one strain of something humans don't have a defense against once for it to run through the population and the posibility of 80%-90% of the population dying is not unheard of from a historical perspective.

  • 3 votes
#1.2 - Tue Jul 17, 2012 4:48 AM EDT

Humans have been manipulating DNA ever since the first humans bred dogs together trying to strengthen traits they found desirable.

Noone is going to try to make a "manpanzee" or a "humanpotomus" As for biological warfare, it's already here and they are trying to deal with it.

Think of this though: If you can protect your computer from viruses ( I can) then you should be able to detect harmful dna code before it is converted into base pairs.

  • 1 vote
#1.3 - Tue Jul 17, 2012 9:14 AM EDT

They are talking about using this to create micro-organisms of just a few cells, not complex organic structures like plants and animals.

    #1.4 - Tue Jul 17, 2012 9:25 AM EDT

    There are too many missing links. If evolution is what you believe in.

    Evolution isn't to be "believed" in. Evolution doesn't much care if you believe in it or not. Evolution happened/happens regardless of what we wish or want to happen.

    As for biological warfare, it's already here and they are trying to deal with it.

    I'm slightly more optimistic about our future. I like to think the more educated we become, the more scientifically literate we become, so too, do we become better human beings ... more cognizant of where we came from and where we are going. I like to think human altruism only gets better with age and wisdom about the natural world.

    Call me naive, but there is plenty of data to back this claim. We've created a progressively more peaceful epoch the further and further we've advanced into the scientific age. "The Better Angels of our Nature" is one of many books that highlight this fact.

    • 4 votes
    #1.5 - Tue Jul 17, 2012 10:36 AM EDT

    They are talking about using this to create micro-organisms of just a few cells, not complex organic structures like plants and animals.

    Exactly my point.

    I'm slightly more optimistic about our future. I like to think the more educated we become, the more scientifically literate we become, so too, do we become better human beings

    We need to be optimistic, and you are right- to an extent. We should continue to be vigilent to people that would use technology to make havoc though.

    • 1 vote
    #1.6 - Tue Jul 17, 2012 10:54 AM EDT

    We should continue to be vigilent to people that would use technology to make havoc though.

    Of course.

    My observation (or maybe it's a hope) is that these people will become fewer and father between, however.

    • 2 votes
    #1.7 - Tue Jul 17, 2012 11:04 AM EDT

    *Farther

    Luke ....

      #1.8 - Tue Jul 17, 2012 11:32 AM EDT
      Reply

      Yikes.

      • 2 votes
      Reply#2 - Tue Jul 17, 2012 2:32 AM EDT

      A new meaning to the "computer virus".

      • 2 votes
      Reply#3 - Tue Jul 17, 2012 6:13 AM EDT

      this was featured last night LazyCash43.com

        Reply#4 - Tue Jul 17, 2012 8:23 AM EDT

        No it wasn't.

          #4.1 - Wed Jul 18, 2012 1:09 AM EDT
          Reply

          Venter's synthetic organisms have a major flaw: they cannot survive stress. Existing bacteria have hundreds of genes that are usually idle but come into action when environmental conditions become unfavorable. Venter's bugs will go belly up when exposed to changes in temperature, pH, nutrients and light, dessication, toxins, freezing, you name it.

          • 3 votes
          Reply#5 - Tue Jul 17, 2012 9:01 AM EDT

          I saw a big beetle in my kitchen today who was belly-up, I had to help him, he couldn't right himself

            #5.1 - Tue Jul 17, 2012 10:31 AM EDT
            Reply

            Is this sanctioned by "LEVIS" or "WRANGLER" .... ??

            • 1 vote
            Reply#6 - Tue Jul 17, 2012 1:42 PM EDT

            SCIENCE IS GREAT!!!!!

            • 1 vote
            Reply#7 - Tue Jul 17, 2012 9:50 PM EDT

            PROBLEMS and PROMISES go together. Automobiles make life easier AND are involved in over 50,000 deaths a year.

            Sort of like one of my lady friends. Beautiful, charming, smart, loving - but you'd better not seriously threaten any of her friends!

              Reply#8 - Wed Jul 18, 2012 7:50 PM EDT
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